Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | PDE4A | P27815 | 2/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634304 | 0.91 | HRH4 (0.38) | HRH4HRH3HTR3AKCNH2 | |
| SCHEMBL13634262 | 0.85 | HRH4 (0.35) | HRH4HRH3LRRK2 | |
| SCHEMBL13634313 | 0.84 | CNR2 (0.37) | HRH4HRH3PDE10A | |
| SCHEMBL13634239 | 0.81 | AOC3 (0.35) | HRH4HRH3CHRM3PDE4APDE4B | |
| SCHEMBL13634240 | 0.80 | HRH4 (0.33) | HRH4HRH3 | |
| SCHEMBL13634305 | 0.80 | GPR119 (0.43) | HRH4HRH3HTR3AKCNH2 | |
| SCHEMBL13634210 | 0.76 | HRH3 (0.33) | HRH4HRH3 | |
| SCHEMBL13634325 | 0.75 | ACACB (0.35) | — | |
| SCHEMBL13612636 | 0.74 | HTR6 (0.44) | HRH4HTR3A | |
| SCHEMBL13634370 | 0.74 | MAPK1 (0.39) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |