Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 8/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.35 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | IKBKB | O14920 | 2/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634305 | 0.91 | GPR119 (0.43) | CNR2IRAK4GPR119HRH4HRH3 | |
| SCHEMBL13634210 | 0.88 | HRH3 (0.33) | HRH4HRH3 | |
| SCHEMBL13634211 | 0.84 | HRH4 (0.39) | HRH4HRH3PDE10A | |
| SCHEMBL13634262 | 0.83 | HRH4 (0.35) | HRH4HRH3 | |
| SCHEMBL13634304 | 0.80 | HRH4 (0.38) | HRH4HRH3 | |
| SCHEMBL13634239 | 0.80 | AOC3 (0.35) | HRH4HRH3PDE10A | |
| SCHEMBL13634240 | 0.79 | HRH4 (0.33) | CNR2HRH4HRH3 | |
| SCHEMBL2770990 | 0.76 | HCRTR1 (0.46) | IRAK4P2RY12 | |
| SCHEMBL13634314 | 0.75 | LIPG (0.37) | HRH4P2RY12 | |
| SCHEMBL13634325 | 0.74 | ACACB (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |