Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.33 |
| ▸ | MTOR | P42345 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.32 |
| ▸ | SMPD3 | Q9NY59 | 2/20 | 0.32 |
| ▸ | CDC7 | O00311 | 1/20 | 0.32 |
| ▸ | PLK4 | O00444 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634313 | 0.91 | CNR2 (0.37) | GPR119HRH4HRH3ALOX5APIRAK4 | |
| SCHEMBL13634304 | 0.86 | HRH4 (0.38) | HRH4HRH3HTR3AKCNH2 | |
| SCHEMBL13634210 | 0.84 | HRH3 (0.33) | HRH4HRH3CDK1CDK2 | |
| SCHEMBL13634262 | 0.80 | HRH4 (0.35) | HRH4HRH3EGFR | |
| SCHEMBL13634211 | 0.80 | HRH4 (0.39) | HRH4HRH3HTR3AKCNH2 | |
| SCHEMBL13162797 | 0.79 | GPR119 (0.46) | GPR119PIK3CAMTORKDM4EALDH1A1 | |
| SCHEMBL13612636 | 0.79 | HTR6 (0.44) | HRH4KDM4EHTR3A | |
| SCHEMBL13634370 | 0.79 | MAPK1 (0.39) | SMN1; SMN2MAPK1KCNH2 | |
| SCHEMBL13634326 | 0.77 | GPR119 (0.34) | GPR119HRH4CNR2 | |
| SCHEMBL13634239 | 0.77 | AOC3 (0.35) | HRH4RAB9APIK3CAMTORHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |