SCHEMBL13634326

SCHEMBL13634326

CCc1coc(N2CCC(OCC3CC3)CC2)n1

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 3/20 0.34
FFAR2 O15552 1/20 0.31
LPL P06858 1/20 0.31
LIPG Q9Y5X9 1/20 0.31
LRRK2 Q5S007 1/20 0.31
HRH4 Q9H3N8 1/20 0.30
CNR2 P34972 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13634240 0.80 HRH4 (0.33) HRH4CNR2
SCHEMBL13634304 0.79 HRH4 (0.38) HRH4
SCHEMBL13634239 0.78 AOC3 (0.35) HRH4
SCHEMBL13162801 0.78 GPR119 (0.34) GPR119
SCHEMBL13634305 0.77 GPR119 (0.43) GPR119HRH4CNR2
SCHEMBL15888606 0.77 HCRTR1 (0.41) GPR119LPLLIPGCNR2
SCHEMBL13634329 0.77 LIPG (0.41) GPR119FFAR2LPLLIPGCNR2
SCHEMBL13634246 0.77 OGA (0.36)
SCHEMBL13634314 0.76 LIPG (0.37) LIPGHRH4
SCHEMBL13634319 0.74 NAAA (0.48)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8304547-B2 Azolecarboxamide compound or salt thereof ASTELLAS PHARMA INC. (JP) 2012-11-06 US disclosed