Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.41 |
| ▸ | LPL | P06858 | 1/20 | 0.41 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.33 |
| ▸ | TTR | P02766 | 3/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | RBP4 | P02753 | 2/20 | 0.32 |
| ▸ | KMO | O15229 | 1/20 | 0.32 |
| ▸ | ACACA | Q13085 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | ITGAL | P20701 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13270741 | 0.87 | LPL (0.35) | LIPGLPLFFAR2GPR119ADRA1A | |
| SCHEMBL3436269 | 0.86 | HCRTR1 (0.35) | LIPGTTRRBP4GSK3BIRAK4 | |
| SCHEMBL15888606 | 0.85 | HCRTR1 (0.41) | LIPGLPLGPR119HCRTR2CNR2 | |
| SCHEMBL13162581 | 0.79 | TTR (0.39) | LIPGLPLTTRIRAK4HCRTR2 | |
| SCHEMBL3436255 | 0.78 | IRAK4 (0.41) | GPR119GSK3BIRAK4ITGAL | |
| SCHEMBL13162585 | 0.78 | IRAK4 (0.37) | RBP4KMOGSK3BIRAK4ITGAL | |
| SCHEMBL13634348 | 0.77 | LIPG (0.41) | LIPGLPLTTRIRAK4HCRTR2 | |
| SCHEMBL13634332 | 0.77 | SCD5 (0.39) | TTRIRAK4 | |
| SCHEMBL13634326 | 0.77 | GPR119 (0.34) | LIPGLPLFFAR2GPR119CNR2 | |
| SCHEMBL13163108 | 0.77 | EPHX2 (0.42) | TTRRBP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |