Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR6 | P46095 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SCD | O00767 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | BCL3 | P20749 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634796 | 0.92 | GPR6 (0.37) | GPR6IRAK4 | |
| SCHEMBL13634553 | 0.92 | BCL3 (0.36) | ALDH1A1IRAK4MAPTMEN1LMNA | |
| SCHEMBL13634745 | 0.92 | BCL3 (0.36) | ALDH1A1IRAK4MAPTMEN1LMNA | |
| SCHEMBL13634890 | 0.88 | ALDH1A1 (0.37) | GPR6ALDH1A1GAAKDM4EIRAK4 | |
| SCHEMBL13634860 | 0.88 | POLB (0.43) | ALDH1A1GAAKDM4EMAPTLMNA | |
| SCHEMBL13634787 | 0.88 | HCAR2 (0.40) | GPR6ALDH1A1KDM4EIRAK4MEN1 | |
| SCHEMBL13270803 | 0.88 | HCAR2 (0.40) | GPR6ALDH1A1KDM4EIRAK4MEN1 | |
| SCHEMBL13634840 | 0.87 | PIM1 (0.37) | GPR6ALDH1A1KDM4EIRAK4L3MBTL1 | |
| SCHEMBL13634625 | 0.86 | MEN1 (0.40) | GPR6ALDH1A1KDM4EIRAK4MEN1 | |
| SCHEMBL13634544 | 0.86 | MEN1 (0.40) | GPR6ALDH1A1KDM4EIRAK4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |