Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | GPR6 | P46095 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13270432 | 0.93 | LMNA (0.36) | ALDH1A1LMNAKMT2APKMGPR6 | |
| SCHEMBL13634505 | 0.92 | PIM1 (0.35) | IRAK4GPR6FGFR1 | |
| SCHEMBL13634860 | 0.90 | POLB (0.43) | ALDH1A1LMNAKMT2ASMN1; SMN2KDM4E | |
| SCHEMBL13270803 | 0.90 | HCAR2 (0.40) | ALDH1A1KMT2AIRAK4GPR6SMN1; SMN2 | |
| SCHEMBL13634787 | 0.90 | HCAR2 (0.40) | ALDH1A1KMT2AIRAK4GPR6SMN1; SMN2 | |
| SCHEMBL13634726 | 0.88 | GPR6 (0.38) | ALDH1A1LMNAKMT2AIRAK4GPR6 | |
| SCHEMBL13634625 | 0.87 | MEN1 (0.40) | ALDH1A1KMT2AIRAK4PKMGPR6 | |
| SCHEMBL13634544 | 0.87 | MEN1 (0.40) | ALDH1A1KMT2AIRAK4PKMGPR6 | |
| SCHEMBL13634553 | 0.86 | BCL3 (0.36) | ALDH1A1LMNAKMT2AIRAK4PKM | |
| SCHEMBL13634745 | 0.86 | BCL3 (0.36) | ALDH1A1LMNAKMT2AIRAK4PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |