Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | VNN1 | O95497 | 1/20 | 0.38 |
| ▸ | SCD | O00767 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.36 |
| ▸ | MTOR | P42345 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.36 |
| ▸ | PIM1 | P11309 | 3/20 | 0.36 |
| ▸ | RHOA | P61586 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634880 | 0.92 | RAB9A (0.40) | RAB9ASCDNPC1MEN1KMT2A | |
| SCHEMBL13634863 | 0.86 | MAP3K7 (0.48) | SCD | |
| SCHEMBL13634547 | 0.85 | MAP3K7 (0.39) | SCDMEN1KMT2APIM1LMNA | |
| SCHEMBL13634882 | 0.85 | MAP3K7 (0.39) | RAB9ASCDNPC1PIM1MAPT | |
| SCHEMBL13634849 | 0.84 | GPR6 (0.41) | RAB9ASCDNPC1PIM1MAPT | |
| SCHEMBL13634881 | 0.84 | NPC1 (0.40) | RAB9ASCDNPC1PIM1MAPT | |
| SCHEMBL13634653 | 0.83 | HRH3 (0.41) | RAB9AHSD17B10SCDNPC1MAPT | |
| SCHEMBL13634883 | 0.79 | NPC1 (0.43) | NPC1PIM1MAPK1 | |
| SCHEMBL13634826 | 0.78 | GPR6 (0.39) | RAB9ASCDNPC1PIM1MAPT | |
| SCHEMBL13634698 | 0.78 | MAP3K7 (0.47) | SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |