Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20687541 | 1.00 | THRA (0.38) | THRATHRB | |
| SCHEMBL25743383 | 0.83 | KMT2A (0.36) | — | |
| SCHEMBL10074434 | 0.83 | KMT2A (0.36) | — | |
| SCHEMBL10198836 | 0.82 | — | — | |
| SCHEMBL20687474 | 0.82 | — | — | |
| SCHEMBL4153538 | 0.82 | — | — | |
| SCHEMBL23488926 | 0.79 | NCF1 (0.38) | — | |
| SCHEMBL21214055 | 0.79 | ESR1 (0.31) | — | |
| SCHEMBL23488979 | 0.79 | NCF1 (0.38) | — | |
| SCHEMBL7155825 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9493412-B2 | Pyrrolinone carboxamide compounds useful as endothelial lipase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2016-11-15 | — | — | US | disclosed |
| US-20140228321-A1 | PYRROLINONE CARBOXAMIDE COMPOUNDS USEFUL AS ENDOTHELIAL LIPASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2014-08-14 | — | — | US | disclosed |
| US-8562953-B2 | Dendritic polymers and magnetic resonance imaging contrast agent employing the same | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2013-10-22 | — | — | US | disclosed |
| US-20130030139-A1 | DENDRITIC POLYMERS AND MAGNETIC RESONANCE IMAGING CONTRAST AGENT EMPLOYING THE SAME | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2013-01-31 | — | — | US | disclosed |
| US-8303937-B2 | Dendritic polymers and magnetic resonance imaging contrast agent employing the same | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2012-11-06 | — | — | US | disclosed |
| US-20090169480-A1 | DENDRITIC POLYMERS AND MAGNETIC RESONANCE IMAGING CONTRAST AGENT EMPLOYING THE SAME | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2009-07-02 | — | — | US | disclosed |
| US-20090169481-A1 | DENDRITIC POLYMERS AND MAGNETIC RESONANCE IMAGING CONTRAST AGENT EMPLOYING THE SAME | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2009-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090169481-A1 | DENDRITIC POLYMERS AND MAGNETIC RESONANCE IMAGING CONTRAST AGENT EMPLOYING THE SAME | DCLK1, MSR1, S1PR3 | THRA 4502/4885THRB 4650/4885 |
| US-20140228321-A1 | PYRROLINONE CARBOXAMIDE COMPOUNDS USEFUL AS ENDOTHELIAL LIPASE INHIBITORS | LIPG, PNLIP, LPL | THRA 4550/4885THRB 4156/4885 |
| US-20090169480-A1 | DENDRITIC POLYMERS AND MAGNETIC RESONANCE IMAGING CONTRAST AGENT EMPLOYING THE SAME | CD14, DCUN1D3, CCR3 | THRA 3177/4885THRB 4028/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.