SCHEMBL756978

SCHEMBL756978

COCCOC(=O)CCC(C)=O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA2A P08913 1/20 0.46
ADRA1A P35348 1/20 0.46
ALDH1A1 P00352 4/20 0.46
MAPT P10636 2/20 0.45
BLM P54132 1/20 0.45
DGKA P23743 1/20 0.43
TSHR P16473 5/20 0.40
LMNA P02545 1/20 0.39
SLC15A2 Q16348 1/20 0.39
MGAM O43451 1/20 0.37
GAA P10253 1/20 0.37
SI P14410 1/20 0.37
MGAM2 Q2M2H8 1/20 0.37
TDP1 Q9NUW8 1/20 0.36
HTR2C P28335 1/20 0.35
DNM1 Q05193 1/20 0.32
PGR P06401 1/20 0.32
CHRM2 P08172 1/20 0.32
CHRM4 P08173 1/20 0.32
HTR1A P08908 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29333715 0.94 ADRA2A (0.42) ADRA2AADRA1AALDH1A1MAPTBLM
SCHEMBL12314639 0.94 ADRA2A (0.42) ADRA2AADRA1AALDH1A1MAPTBLM
SCHEMBL813361 0.91 ADRA2A (0.54) ADRA2AADRA1AALDH1A1MAPTBLM
SCHEMBL13635974 0.91 ALDH1A1 (0.56) ADRA2AADRA1AALDH1A1MAPTBLM
Propene SCHEMBL12971206 0.90 ADRA2A (0.39) ADRA2AADRA1AALDH1A1MAPTBLM
SCHEMBL15131901 0.87 DGKA (0.50) ADRA2AADRA1AALDH1A1MAPTBLM
SCHEMBL14434076 0.87 DGKA (0.55) ADRA2AADRA1AALDH1A1MAPTBLM
SCHEMBL14296732 0.87 ADRA2A (0.43) ADRA2AADRA1AALDH1A1MAPTBLM
SCHEMBL11997756 0.87 ALDH1A1 (0.47) ADRA2AADRA1AALDH1A1MAPTBLM
SCHEMBL14579714 0.86 MAPT (0.46) ALDH1A1MAPTTSHRLMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113767097-B Prodrugs of caspase inhibitors 株式会社LG化学 2025-03-14 CN disclosed
EP-3994117-B1 HYDROGENATION OF ESTERS TO ALCOHOLS IN THE PRESENCE OF A RU-PNN COMPLEX BASF SE (DE) 2024-07-03 EP disclosed
US-11911521-B2 Antibacterial nanofiber UNIVERSITY OF MANITOBA (CA) 2024-02-27 US disclosed
US-11791459-B2 Electrochemically active materials and methods of preparing the same ENEVATE CORPORATION (US) 2023-10-17 US disclosed
US-11767467-B2 Photochromic compound and curable composition containing said photochromic compound TOKUYAMA CORPORATION (JP) 2023-09-26 US disclosed
US-20230280500-A1 PHOTOCHROMIC COMPOUND, PHOTOCHROMIC CURABLE COMPOSITION, CURED BODY, LENS AND EYEGLASSES TOKUYAMA CORPORATION (JP) 2023-09-07 US disclosed
US-20230242809-A1 PHOTOCHROMIC HYDROXYURETHANE COMPOUND TOKUYAMA CORPORATION (JP) 2023-08-03 US disclosed
US-20230242809-A1 PHOTOCHROMIC HYDROXYURETHANE COMPOUND TOKUYAMA CORPORATION (JP) 2023-08-03 US disclosed
US-11708316-B2 Hydrogenation of esters to alcohols in the presence of a Ru-PNN complex BASF SE (DE) 2023-07-25 US disclosed
US-11708316-B2 Hydrogenation of esters to alcohols in the presence of a Ru-PNN complex BASF SE (DE) 2023-07-25 US disclosed
US-20110150837-A1 Amphiphilic polymer functionalized by methionine FLAMEL TECHNOLOGIES (FR) 2011-06-23 US disclosed
US-20110082264-A1 TRANSKETALIZED COMPOSITIONS, SYNTHESIS, AND APPLICATIONS SEGETIS, INC. (US) 2011-04-07 US disclosed
US-20110076423-A1 CELLULOSE ACYLATE FILM, RETARDATION FILM, POLARIZER AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed
WO-2009146202-A2 TRANSKETALIZED COMPOSITIONS, SYNTHESIS, AND APPLICATIONS SEGETIS, INC. (US) 2009-12-03 WO disclosed
US-20090203703-A1 Thienopyrimidine Derivatives ASKA PHARMACEUTICAL CO., LTD. (JP) 2009-08-13 US disclosed
US-20090192113-A1 Interfering RNA Duplex Having Blunt-Ends and 3`-Modifications WEILER JAN 2009-07-30 US disclosed
US-20090047270-A1 ENZYMATIC ANTICANCER THERAPY ENZON PHARMACEUTICALS, INC. (US) 2009-02-19 US disclosed
US-20090047271-A1 STABLE RECOMBINANT ADENOSINE DEAMINASE ENZON PHARMACEUTICALS, INC. (US) 2009-02-19 US disclosed
EP-1908765-A1 THIENOPYRIMIDINE DERIVATIVE ASKA Pharmaceutical Co., Ltd. (JP) 2008-04-09 EP disclosed
US-7301041-B2 Bi-functional metallocenes, preparation process and use in the labeling or biological molecules BIO MERIEUX (FR) 2007-11-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11911521-B2 Antibacterial nanofiber AADAC, USP39, DLAT ADRA2A 4741/4885ADRA1A 4761/4885ALDH1A1 3377/4885
US-20090047270-A1 ENZYMATIC ANTICANCER THERAPY RNASE1, ADA, DCTD ADRA2A 3322/4885ADRA1A 3332/4885ALDH1A1 140/4885
US-20110150837-A1 Amphiphilic polymer functionalized by methionine MTR, LNPEP, METAP1 ADRA2A 2376/4885ADRA1A 2046/4885ALDH1A1 3801/4885
US-20090047271-A1 STABLE RECOMBINANT ADENOSINE DEAMINASE ADA, CDA, DCTD ADRA2A 2035/4885ADRA1A 2051/4885ALDH1A1 105/4885
US-20110082264-A1 TRANSKETALIZED COMPOSITIONS, SYNTHESIS, AND APPLICATIONS TKT, KHK, KYAT3 ADRA2A 4577/4885ADRA1A 4582/4885ALDH1A1 2261/4885
US-20090203703-A1 Thienopyrimidine Derivatives PDE9A, BPHL, THOP1 ADRA2A 1110/4885ADRA1A 1020/4885ALDH1A1 2303/4885
US-11708316-B2 Hydrogenation of esters to alcohols in the presence of a Ru-PNN complex ADH1A, PNN, ADH1C ADRA2A 1882/4885ADRA1A 986/4885ALDH1A1 103/4885
US-20090192113-A1 Interfering RNA Duplex Having Blunt-Ends and 3`-Modifications NSUN3, NSUN2, RNGTT ADRA2A 1910/4885ADRA1A 1534/4885ALDH1A1 3068/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.