SCHEMBL13636792

SCHEMBL13636792

CC1(C)OB(c2cccc(/C=C/c3ccc(N(c4ccc(/C=C/c5ccc(F)cc5)cc4)c4ccc(/C=C/c5ccc(F)cc5)cc4)cc3)c2)OC1(C)C

nearest known ligand 0.44

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LPL P06858 3/20 0.44
LIPG Q9Y5X9 3/20 0.44
NFE2L2 Q16236 10/20 0.44
APP P05067 3/20 0.41
P4HB P07237 1/20 0.38
RELA Q04206 1/20 0.36
MAT2A P31153 1/20 0.34
KCNH2 Q12809 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13636790 0.94 LIPG (0.45) LPLLIPGNFE2L2APPP4HB
SCHEMBL13636793 0.89 NFE2L2 (0.42) LPLLIPGNFE2L2APPP4HB
SCHEMBL13636800 0.87 NFE2L2 (0.42) LPLLIPGNFE2L2APPP4HB
SCHEMBL13636794 0.85 LIPG (0.39) LPLLIPGNFE2L2APPP4HB
SCHEMBL13636787 0.79 P4HB (0.51) LPLLIPGP4HBRELA
SCHEMBL13855293 0.79 P4HB (0.51) LPLLIPGP4HBRELA
SCHEMBL23988619 0.78 LPL (0.71) LPLLIPGP4HB
SCHEMBL15481281 0.78 LPL (0.71) LPLLIPGNFE2L2APPP4HB
SCHEMBL20671247 0.78 LPL (0.71) LPLLIPGP4HB
SCHEMBL16352626 0.78 LPL (0.71) LPLLIPGP4HB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8785001-B2 Organic electroluminescent devices MERCK PATENT GMBH (DE) 2014-07-22 US disclosed
US-8785001-B2 Organic electroluminescent devices MERCK PATENT GMBH (DE) 2014-07-22 US disclosed
US-8304095-B2 Organic electroluminescent devices MERCK PATENT GMBH (DE) 2012-11-06 US disclosed
US-8304095-B2 Organic electroluminescent devices MERCK PATENT GMBH (DE) 2012-11-06 US disclosed
US-20080297037-A1 Organic Electroluminescent Devices MERCK PATENT GMBH (DE) 2008-12-04 US disclosed
US-20080297037-A1 Organic Electroluminescent Devices MERCK PATENT GMBH (DE) 2008-12-04 US disclosed
US-20080272693-A1 Organic Electroluminescent Devices MERCK PATENT GMBH (DE) 2008-11-06 US disclosed
US-20080272693-A1 Organic Electroluminescent Devices MERCK PATENT GMBH (DE) 2008-11-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080272693-A1 Organic Electroluminescent Devices EML4, MT-ND4L, EPCAM LPL 684/4885LIPG 1058/4885NFE2L2 423/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.