Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.42 |
| ▸ | LPL | P06858 | 5/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 5/20 | 0.41 |
| ▸ | P4HB | P07237 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 3/20 | 0.37 |
| ▸ | RELA | Q04206 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13636790 | 0.95 | LIPG (0.45) | NFE2L2LPLLIPGP4HBAPP | |
| SCHEMBL13636792 | 0.89 | LPL (0.44) | NFE2L2LPLLIPGP4HBAPP | |
| SCHEMBL13636794 | 0.86 | LIPG (0.39) | NFE2L2LPLLIPGP4HBAPP | |
| SCHEMBL13636800 | 0.85 | NFE2L2 (0.42) | NFE2L2LPLLIPGP4HBAPP | |
| SCHEMBL12000718 | 0.84 | LIPG (0.47) | LPLLIPGHIF1AIRAK4 | |
| SCHEMBL17167121 | 0.82 | NFE2L2 (0.40) | NFE2L2APPRELAKDM4EHPGD | |
| SCHEMBL13979251 | 0.81 | P4HB (0.36) | LPLLIPGP4HBHPGDHIF1A | |
| SCHEMBL13855293 | 0.80 | P4HB (0.51) | LPLLIPGP4HBRELA | |
| SCHEMBL13636787 | 0.80 | P4HB (0.51) | LPLLIPGP4HBRELA | |
| SCHEMBL4402172 | 0.79 | NFE2L2 (0.59) | NFE2L2APPRELAALOX5PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8785001-B2 | Organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2014-07-22 | — | — | US | disclosed |
| US-8785001-B2 | Organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2014-07-22 | — | — | US | disclosed |
| US-8304095-B2 | Organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2012-11-06 | — | — | US | disclosed |
| US-8304095-B2 | Organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2012-11-06 | — | — | US | disclosed |
| US-20080297037-A1 | Organic Electroluminescent Devices | MERCK PATENT GMBH (DE) | 2008-12-04 | — | — | US | disclosed |
| US-20080297037-A1 | Organic Electroluminescent Devices | MERCK PATENT GMBH (DE) | 2008-12-04 | — | — | US | disclosed |
| US-20080272693-A1 | Organic Electroluminescent Devices | MERCK PATENT GMBH (DE) | 2008-11-06 | — | — | US | disclosed |
| US-20080272693-A1 | Organic Electroluminescent Devices | MERCK PATENT GMBH (DE) | 2008-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080272693-A1 | Organic Electroluminescent Devices | EML4, MT-ND4L, EPCAM | NFE2L2 423/4885LPL 684/4885LIPG 1058/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.