Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 4/20 | 0.46 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | LOX | P28300 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24359749 | 0.87 | L3MBTL1 (0.52) | TDP1KMT2ASLC6A2SLC6A3NPSR1 | |
| SCHEMBL24414106 | 0.84 | TDP1 (0.50) | TDP1KMT2ASLC6A2SLC6A3NPSR1 | |
| SCHEMBL8945534 | 0.82 | TDP1 (0.60) | TDP1KMT2ASLC6A2SLC6A3NPSR1 | |
| SCHEMBL25591895 | 0.81 | SMN1; SMN2 (0.54) | TDP1KMT2ASLC6A2SLC6A3NPSR1 | |
| SCHEMBL18607390 | 0.81 | PKM (0.52) | TDP1KMT2ASLC6A2SLC6A3NPSR1 | |
| SCHEMBL8945285 | 0.81 | KDM5A (0.56) | TDP1KMT2ASLC6A2SLC6A3NPSR1 | |
| SCHEMBL24360100 | 0.79 | PKM (0.53) | TDP1KMT2ASLC6A2SLC6A3NPSR1 | |
| SCHEMBL2706447 | 0.79 | PKM (0.71) | TDP1KMT2ASLC6A2SLC6A3NPSR1 | |
| SCHEMBL30711263 | 0.79 | PKM (0.71) | TDP1KMT2ASLC6A2SLC6A3NPSR1 | |
| SCHEMBL24359928 | 0.78 | PKM (0.49) | TDP1KMT2ASLC6A2SLC6A3NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090275515-A1 | 2-HYDROXY-2-PHENYLTHIOPHENYLPROPIONAMIDES AS ANDROGEN RECEPTOR MODULATORS | MERCK SHARP & DOHME CORP. | 2009-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275515-A1 | 2-HYDROXY-2-PHENYLTHIOPHENYLPROPIONAMIDES AS ANDROGEN RECEPTOR MODULATORS | SHBG, AR, FSHR | TDP1 530/4885KMT2A 308/4885SLC6A2 4655/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.