Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | LGMN | Q99538 | 1/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.37 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634374 | 0.90 | ALDH1A1 (0.43) | ALDH1A1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL13638973 | 0.81 | GRM2 (0.49) | ALDH1A1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL9344830 | 0.79 | LGMN (0.54) | ALDH1A1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL31642763 | 0.77 | IP6K1 (0.38) | ALDH1A1KDM4EMAPTGAAIP6K1 | |
| SCHEMBL31642606 | 0.76 | LGMN (0.36) | ALDH1A1KDM4ELRRK2SYKFFAR2 | |
| SCHEMBL13634232 | 0.74 | SIRT6 (0.61) | ALDH1A1MAPTHPGDSIRT6SMN1; SMN2 | |
| SCHEMBL26783647 | 0.74 | ALDH1A1 (0.43) | ALDH1A1KDM4ECHEK1 | |
| SCHEMBL20509930 | 0.74 | IP6K1 (0.68) | ALDH1A1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL13162590 | 0.74 | SYK (0.46) | ALDH1A1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL40467 | 0.73 | IP6K1 (0.66) | ALDH1A1KDM4EMAPTHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |