Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.49 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13638959 | 0.88 | SIGMAR1 (0.52) | L3MBTL3HRH3SIGMAR1CYP1A2KCNJ1 | |
| SCHEMBL28135835 | 0.77 | HRH3 (0.49) | L3MBTL1MBTD1L3MBTL3HRH3SIGMAR1 | |
| SCHEMBL13638957 | 0.74 | HRH3 (0.49) | HRH3KCNJ1 | |
| SCHEMBL1958869 | 0.74 | SIGMAR1 (0.50) | L3MBTL1MBTD1L3MBTL3HRH3SIGMAR1 | |
| SCHEMBL13638857 | 0.72 | ALDH1A1 (0.47) | L3MBTL1HRH3 | |
| SCHEMBL20961917 | 0.72 | ALDH1A1 (0.40) | L3MBTL1CYP1A2 | |
| SCHEMBL28628177 | 0.72 | HRH3 (0.61) | L3MBTL1MBTD1L3MBTL3HRH3SIGMAR1 | |
| SCHEMBL13959545 | 0.70 | HRH3 (0.65) | L3MBTL1MBTD1L3MBTL3HRH3SIGMAR1 | |
| SCHEMBL17538318 | 0.70 | HRH3 (0.59) | L3MBTL1MBTD1L3MBTL3HRH3SIGMAR1 | |
| SCHEMBL13638971 | 0.70 | SIGMAR1 (0.43) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |