Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.52 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | ERN1 | O75460 | 2/20 | 0.39 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13638957 | 0.88 | HRH3 (0.49) | KCNJ1ERN1HRH3 | |
| SCHEMBL13638834 | 0.88 | L3MBTL1 (0.49) | SIGMAR1KCNJ1KCNH2L3MBTL3HRH3 | |
| SCHEMBL13889918 | 0.74 | SIGMAR1 (0.40) | SIGMAR1POLBLTA4H | |
| SCHEMBL13662563 | 0.74 | SIGMAR1 (0.55) | SIGMAR1KCNJ1KCNH2L3MBTL3HRH3 | |
| SCHEMBL6222223 | 0.74 | SIGMAR1 (0.55) | SIGMAR1KCNJ1KCNH2L3MBTL3HRH3 | |
| SCHEMBL6224362 | 0.73 | SIGMAR1 (0.55) | SIGMAR1HRH3POLB | |
| SCHEMBL13638752 | 0.73 | GRM2 (0.43) | KCNH2 | |
| SCHEMBL13638739 | 0.72 | GRM2 (0.42) | KCNJ1ERN1MEN1KMT2A | |
| SCHEMBL19603341 | 0.70 | ERN1 (0.51) | ERN1HRH3POLB | |
| SCHEMBL13638749 | 0.69 | KMT2A (0.54) | HRH3POLBCYP2D6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |