Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 4/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.37 |
| ▸ | BACE1 | P56817 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13638957 | 0.81 | HRH3 (0.49) | ALDH1A1KDM4ERAB9ANPC1HRH3 | |
| SCHEMBL13638971 | 0.79 | SIGMAR1 (0.43) | ALDH1A1MEN1KMT2ADRD2DRD4 | |
| SCHEMBL13638748 | 0.77 | ADORA2A (0.35) | ACHE | |
| SCHEMBL13638752 | 0.74 | GRM2 (0.43) | GRM2DRD4 | |
| SCHEMBL13638834 | 0.72 | L3MBTL1 (0.49) | HRH3L3MBTL1 | |
| SCHEMBL13638859 | 0.71 | HDAC8 (0.51) | ALDH1A1ACHEHRH3 | |
| SCHEMBL20961917 | 0.70 | ALDH1A1 (0.40) | ALDH1A1KDM4EPOLBRAB9AMEN1 | |
| SCHEMBL13638876 | 0.69 | DRD4 (0.49) | GRM2DRD2DRD4 | |
| SCHEMBL13638959 | 0.69 | SIGMAR1 (0.52) | POLBMEN1CYP2D6KMT2AHRH3 | |
| SCHEMBL2559897 | 0.69 | KDM4E (0.47) | ALDH1A1KDM4EHRH3LTA4HL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |