Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 2/20 | 0.37 |
| ▸ | CDK8 | P49336 | 2/20 | 0.37 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.35 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.34 |
| ▸ | BRAF | P15056 | 3/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.32 |
| ▸ | PDE7B | Q9NP56 | 4/20 | 0.31 |
| ▸ | DGKZ | Q13574 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13638971 | 0.73 | SIGMAR1 (0.43) | — | |
| SCHEMBL13638752 | 0.71 | GRM2 (0.43) | CCNCCDK8PRMT5WDR77 | |
| SCHEMBL13270625 | 0.70 | CCNC (0.40) | CCNCCDK8PDE1BJAK2JAK1 | |
| SCHEMBL1929059 | 0.70 | JAK2 (0.43) | CCNCCDK8PDE1BJAK2JAK1 | |
| SCHEMBL15312373 | 0.70 | TLR7 (0.45) | CCNCCDK8PDE1BJAK2JAK1 | |
| SCHEMBL9953012 | 0.70 | TLR7 (0.45) | CCNCCDK8PDE1BJAK2JAK1 | |
| SCHEMBL15324898 | 0.70 | TLR7 (0.43) | CCNCCDK8PDE1BJAK2JAK1 | |
| SCHEMBL22425610 | 0.70 | TLR7 (0.43) | CCNCCDK8PDE1BJAK2JAK1 | |
| SCHEMBL13638957 | 0.70 | HRH3 (0.49) | — | |
| SCHEMBL13638748 | 0.69 | ADORA2A (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |