Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9945918 | 0.81 | L3MBTL1 (0.46) | ALDH1A1MAPTPOLBLMNATRPA1 | |
| SCHEMBL13623380 | 0.79 | KMT2A (0.43) | ALDH1A1LMNASLC6A2SMN1; SMN2L3MBTL1 | |
| SCHEMBL20150593 | 0.78 | MRGPRX4 (0.42) | ALDH1A1MAPTPOLBSLC6A2KDM4E | |
| SCHEMBL9945954 | 0.77 | ALDH1A1 (0.48) | ALDH1A1MAPTPOLBLMNATRPA1 | |
| SCHEMBL12952630 | 0.74 | ALDH1A1 (0.50) | ALDH1A1MAPTPOLBSMN1; SMN2NPBWR1 | |
| SCHEMBL24133302 | 0.73 | LMNA (0.40) | ALDH1A1MAPTPOLBLMNATRPA1 | |
| SCHEMBL25195625 | 0.73 | ALDH1A1 (0.51) | ALDH1A1MAPTPOLBSMN1; SMN2NPBWR1 | |
| SCHEMBL18959732 | 0.72 | ALDH1A1 (0.47) | ALDH1A1LMNATRPA1CHRM1SLC6A2 | |
| SCHEMBL18959733 | 0.72 | ALDH1A1 (0.45) | ALDH1A1MAPTPOLBSMN1; SMN2NPBWR1 | |
| SCHEMBL11010571 | 0.72 | LMNA (0.48) | ALDH1A1POLBLMNATRPA1CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120283335-A1 | Analogs of Propofol, Preparation Thereof and Use as Anesthetics | SIGNATURE THERAPEUTICS, INC. | 2012-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120283335-A1 | Analogs of Propofol, Preparation Thereof and Use as Anesthetics | GABRP, CYP4F11, CYP2F1 | ALDH1A1 328/4885MAPT 3638/4885POLB 3108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.