Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18959733 | 0.84 | ALDH1A1 (0.45) | ALDH1A1KDM4ETDP1SMN1; SMN2HPGD | |
| SCHEMBL9945918 | 0.83 | L3MBTL1 (0.46) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL17034855 | 0.81 | GAA (0.40) | LMNAALDH1A1SMN1; SMN2HPGDMAPT | |
| SCHEMBL282475 | 0.81 | ALDH1A1 (0.47) | LMNAALDH1A1KDM4ETDP1SMN1; SMN2 | |
| SCHEMBL29970124 | 0.81 | GABRA1 (0.37) | LMNAALDH1A1SMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL19617651 | 0.81 | GABRA1 (0.37) | LMNAALDH1A1SMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL27645331 | 0.81 | GAA (0.45) | LMNAALDH1A1KDM4ETDP1L3MBTL1 | |
| SCHEMBL22320321 | 0.80 | PTGDR2 (0.40) | KDM4EHPGDL3MBTL1MEN1KMT2A | |
| SCHEMBL11890520 | 0.79 | ACHE (0.52) | ACHEALDH1A1KDM4ETDP1SMN1; SMN2 | |
| SCHEMBL30802160 | 0.79 | ACHE (0.52) | ACHEALDH1A1KDM4ETDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230242473-A1 | THYROMIMETICS | AUTOBAHN THERAPEUTICS, INC. | 2023-08-03 | — | — | US | disclosed |
| US-20230242471-A1 | THYROMIMETICS | AUTOBAHN THERAPEUTICS, INC. | 2023-08-03 | — | — | US | disclosed |
| EP-3936497-A1 | PROCESS FOR THE PREPARATION OF DERIVATIVES OF SOBETIROME | Oregon Health & Science University (US) | 2022-01-12 | — | — | EP | disclosed |
| WO-2021257804-A1 | THYROMIMETICS | AUTOBAHN THERAPEUTICS, INC. (US) | 2021-12-23 | — | — | WO | disclosed |
| WO-2021257834-A1 | THYROMIMETICS | AUTOBAHN THERAPEUTICS, INC. (US) | 2021-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230242473-A1 | THYROMIMETICS | TPO, THOP1, THRB | LMNA 1686/4885TRPA1 3369/4885CHRM1 139/4885 |
| US-20230242471-A1 | THYROMIMETICS | TPO, THOP1, THRB | LMNA 1814/4885TRPA1 3317/4885CHRM1 122/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.