Sugi Predict

Sugi Predict / Compounds / SCHEMBL13640312

SCHEMBL13640312

SCHEMBL13640312

CCOP(=O)(Cc1cccc(Br)n1)OCC

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ PGK1 P00558 1/20 0.41
▸ PGK2 P07205 1/20 0.41
▸ NPY5R Q15761 1/20 0.36
▸ KDM4E B2RXH2 1/20 0.36
▸ LMNA P02545 1/20 0.36
▸ HPGD P15428 1/20 0.36
▸ TSHR P16473 1/20 0.35
▸ NPSR1 Q6W5P4 1/20 0.34
▸ MBOAT4 Q96T53 1/20 0.34
▸ CHRNB2 P17787 1/20 0.34
▸ CHRNA4 P43681 1/20 0.34
▸ GRM5 P41594 1/20 0.33
▸ KCNH2 Q12809 1/20 0.33
▸ HTR7 P34969 1/20 0.33
▸ CCNT1 O60563 1/20 0.33
▸ CDK9 P50750 1/20 0.33
▸ PARP1 P09874 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30669248 1.00 PGK1 (0.41) PGK1PGK2NPY5RKDM4ELMNA
SCHEMBL5010543 0.88 PGK1 (0.52) PGK1PGK2NPY5RKDM4ELMNA
SCHEMBL26972709 0.86 PGK1 (0.40) PGK1PGK2KDM4ELMNAHPGD
SCHEMBL26738626 0.83 PGK1 (0.40) PGK1PGK2NPY5RKDM4ELMNA
SCHEMBL29427027 0.83 PGK1 (0.40) PGK1PGK2NPY5RKDM4ELMNA
SCHEMBL13217635 0.77 PGK1 (0.38) PGK1PGK2NPY5RKDM4ELMNA
SCHEMBL13199943 0.77 PGK1 (0.38) PGK1PGK2NPY5RKDM4ELMNA
SCHEMBL16524089 0.76 MAPT (0.35) NPY5RKDM4ELMNATSHR
SCHEMBL5021640 0.76 TSHR (0.34) NPY5RKDM4EHPGDTSHRNPSR1
SCHEMBL3510117 0.75 PGK1 (0.42) PGK1PGK2HPGDMBOAT4CHRNB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11858910-B2 Pyridinylmethylenepiperidine derivatives and uses thereof SUNSHINE LAKE PHARMA CO., LTD. (CN) 2024-01-02 — — US disclosed
US-11858910-B2 Pyridinylmethylenepiperidine derivatives and uses thereof SUNSHINE LAKE PHARMA CO., LTD. (CN) 2024-01-02 — — US disclosed
US-RE49735-E1 Oxazolidinones as modulators of MGLUR5 BRISTOL-MYERS SQUIBB COMPANY (US) 2023-11-28 — — US disclosed
US-RE49735-E1 Oxazolidinones as modulators of MGLUR5 BRISTOL-MYERS SQUIBB COMPANY (US) 2023-11-28 — — US disclosed
US-RE49735-E1 Oxazolidinones as modulators of MGLUR5 BRISTOL-MYERS SQUIBB COMPANY (US) 2023-11-28 — — US disclosed
CN-107567443-B Biaryl derivatives as GPR120 agonists 株式会社LG化学 2023-04-28 — — CN disclosed
CN-115925679-A Biaryl derivatives as GPR120 agonists 株式会社LG化学 2023-04-07 — — CN disclosed
EP-3239143-B1 BIARYL DERIVATIVE AS GPR120 AGONIST LG CHEMICAL LTD (KR) 2023-03-22 — — EP disclosed
US-20220135574-A1 BIARYL DERIVATIVE AS GPR120 AGONIST LG CHEM, LTD. (KR) 2022-05-05 — — US disclosed
US-11261186-B2 Biaryl derivative as GPR120 agonist LG CHEM. LTD. (KR) 2022-03-01 — — US disclosed
US-10221138-B2 Biaryl derivatives as GPR120 agonists LG CHEM, LTD. (KR) 2019-03-05 — — US disclosed
US-20170349594-A1 BIARYL DERIVATIVE AS GPR120 AGONIST LG CHEM, LTD. (KR) 2017-12-07 — — US disclosed
EP-3239143-A2 BIARYL DERIVATIVE AS GPR120 AGONIST LG Chem, Ltd. (KR) 2017-11-01 — — EP disclosed
US-20160168096-A1 BIARYL DERIVATIVES AS GPR120 AGONISTS LG LIFE SCIENCES LTD. (KR) 2016-06-16 — — US disclosed
EP-3013796-A1 BIARYL DERIVATIVES AS GPR120 AGONISTS LG Life Sciences Ltd. (KR) 2016-05-04 — — EP disclosed
WO-2014209034-A1 BIARYL DERIVATIVES AS GPR120 AGONISTS LG LIFE SCIENCES LTD. (KR) 2014-12-31 — — WO disclosed
US-8691821-B2 Oxazolidinones as modulators of mGluR5 BRISTOL-MYERS SQUIBB COMPANY (US) 2014-04-08 — — US disclosed
US-8691821-B2 Oxazolidinones as modulators of mGluR5 BRISTOL-MYERS SQUIBB COMPANY (US) 2014-04-08 — — US disclosed
US-20120283264-A1 Oxazolidinones as Modulators of MGLUR5 BRISTOL-MYERS SQUIBB COMPANY 2012-11-08 — — US disclosed
US-20120283264-A1 Oxazolidinones as Modulators of MGLUR5 BRISTOL-MYERS SQUIBB COMPANY 2012-11-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220135574-A1 BIARYL DERIVATIVE AS GPR120 AGONIST GPR119, GLP1R, GIPR PGK1 1649/4885PGK2 1299/4885NPY5R 294/4885
US-11858910-B2 Pyridinylmethylenepiperidine derivatives and uses thereof HTR1F, HTR1A, HTR5A PGK1 674/4885PGK2 732/4885NPY5R 42/4885
US-20160168096-A1 BIARYL DERIVATIVES AS GPR120 AGONISTS GPR119, GLP1R, GIPR PGK1 1615/4885PGK2 1261/4885NPY5R 272/4885
US-20120283264-A1 Oxazolidinones as Modulators of MGLUR5 GRM5, GRIK5, GRM1 PGK1 1141/4885PGK2 1007/4885NPY5R 56/4885
US-10221138-B2 Biaryl derivatives as GPR120 agonists GPR119, GLP1R, GIPR PGK1 1615/4885PGK2 1261/4885NPY5R 272/4885
US-20170349594-A1 BIARYL DERIVATIVE AS GPR120 AGONIST GPR119, GLP1R, GIPR PGK1 1649/4885PGK2 1299/4885NPY5R 294/4885
US-11261186-B2 Biaryl derivative as GPR120 agonist GPR119, GPR88, FFAR1 PGK1 1508/4885PGK2 1263/4885NPY5R 431/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.