Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 10/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13655085 | 0.86 | MAPT (0.47) | GRM5CYP2C9KDM4EMEN1NPC1 | |
| SCHEMBL13655360 | 0.73 | PTGES (0.38) | GRM5KCNH2MEN1KMT2AABL1 | |
| SCHEMBL28705276 | 0.73 | CYP2C9 (0.63) | GRM5KCNH2CYP2C9KDM4EMEN1 | |
| SCHEMBL29429000 | 0.73 | CYP2C9 (0.63) | GRM5KCNH2CYP2C9KDM4EMEN1 | |
| SCHEMBL13655366 | 0.71 | HTR5A (0.36) | — | |
| SCHEMBL13655361 | 0.68 | MAPT (0.43) | GRM5CYP2C9KDM4EMEN1NPC1 | |
| SCHEMBL30707869 | 0.66 | KCNH2 (0.67) | GRM5KCNH2CYP2C9ALDH1A1PTGDR2 | |
| SCHEMBL4562631 | 0.66 | KCNH2 (0.67) | GRM5KCNH2CYP2C9ALDH1A1PTGDR2 | |
| SCHEMBL29120762 | 0.64 | KCNH2 (0.49) | GRM5KCNH2CYP2C9KDM4EMEN1 | |
| SCHEMBL29785704 | 0.64 | KCNH2 (0.49) | GRM5KCNH2CYP2C9KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009123753-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-PHENYL DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-10-08 | — | — | WO | disclosed |