SCHEMBL13660339

SCHEMBL13660339

CC(C)(CNC(=O)C(Cl)(Cl)Cl)CNC(=O)C(Cl)(Cl)Cl

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.42
HSD17B10 Q99714 1/20 0.42
TSHR P16473 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.35
LMNA P02545 3/20 0.34
TP53 P04637 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
MAPT P10636 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
HTT P42858 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
GPR55 Q9Y2T6 1/20 0.33
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14008195 0.85 SMN1; SMN2 (0.36) SMN1; SMN2HSD17B10TSHRL3MBTL1LMNA
SCHEMBL13660342 0.81 LMNA (0.36) L3MBTL1LMNA
SCHEMBL24574899 0.79 SMN1; SMN2 (0.45) SMN1; SMN2HSD17B10TSHRL3MBTL1LMNA
SCHEMBL988057 0.79 LMNA (0.36) TSHRL3MBTL1LMNATP53ALDH1A1
SCHEMBL22472035 0.75 SMN1; SMN2 (0.39) SMN1; SMN2L3MBTL1LMNAHTTALDH1A1
SCHEMBL6253692 0.75 SMN1; SMN2 (0.42) SMN1; SMN2HSD17B10TSHRL3MBTL1LMNA
SCHEMBL6592214 0.74
SCHEMBL14114348 0.72 L3MBTL1 (0.32) HSD17B10L3MBTL1LMNA
SCHEMBL22758126 0.71 SMN1; SMN2 (0.39) SMN1; SMN2HSD17B10TSHRLMNATP53
SCHEMBL14289344 0.71 SMN1; SMN2 (0.39) SMN1; SMN2HSD17B10TSHRLMNATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090263744-A1 ETHYLENICALLY UNSATURATED COMPOUND, LIGHT SENSITIVE COMPOSITION, LIGHT SENSITIVE PLANOGRAPHIC PRINTING PLATE MATERIAL AND PRINTING PROCESS EMPLOYING THE SAME KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2009-10-22 US disclosed
US-20090263744-A1 ETHYLENICALLY UNSATURATED COMPOUND, LIGHT SENSITIVE COMPOSITION, LIGHT SENSITIVE PLANOGRAPHIC PRINTING PLATE MATERIAL AND PRINTING PROCESS EMPLOYING THE SAME KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2009-10-22 US disclosed
US-20090042134-A1 Photosensitive composition, photosensitive planographic printing plate material, and image forming method of photosensitive planographic printing plate material KONICA MINOLTA MEDICAL & GRAPHIC INC. (JP) 2009-02-12 US disclosed
US-20090042134-A1 Photosensitive composition, photosensitive planographic printing plate material, and image forming method of photosensitive planographic printing plate material KONICA MINOLTA MEDICAL & GRAPHIC INC. (JP) 2009-02-12 US disclosed
US-20080274425-A1 Multilayeer; aluminum support with fluoroalkyl acrylic group containing polymer; alkali soluble resin and an acid generator KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-11-06 US disclosed
US-20080274425-A1 Multilayeer; aluminum support with fluoroalkyl acrylic group containing polymer; alkali soluble resin and an acid generator KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-11-06 US disclosed
US-20080182202-A1 Planographic printing plate material and resin used therein KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-07-31 US disclosed
US-20080182202-A1 Planographic printing plate material and resin used therein KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-07-31 US disclosed
US-20080160445-A1 Planographic printing plate material, and method of preparing planographic printing plate employing the same KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-07-03 US disclosed
US-20080160445-A1 Planographic printing plate material, and method of preparing planographic printing plate employing the same KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-07-03 US disclosed
US-7273692-B2 Planographic printing plate material and planographic printing plate preparing process KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-09-25 US disclosed
US-7273692-B2 Planographic printing plate material and planographic printing plate preparing process KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-09-25 US disclosed
US-7252926-B2 Planographic printing plate material and preparing process of planographic printing plate KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-08-07 US disclosed
US-7252926-B2 Planographic printing plate material and preparing process of planographic printing plate KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-08-07 US disclosed
US-7172851-B2 Light sensitive composition, planographic printing plate material, and image formation method KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-02-06 US disclosed
US-7172851-B2 Light sensitive composition, planographic printing plate material, and image formation method KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-02-06 US disclosed
US-20070020555-A1 Photosensitive composition, photosensitive lithography plate and method for producing lithography plate KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-01-25 US disclosed
US-20070020555-A1 Photosensitive composition, photosensitive lithography plate and method for producing lithography plate KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-01-25 US disclosed
US-20070015086-A1 Photosensitive composition, photosensitive planographic printing plate material, and image forming method of photosensitive planographic printing plate material KONICA MINOLTA MEDICAL & GRAPHIC, INC. 2007-01-18 US disclosed
US-20070015086-A1 Photosensitive composition, photosensitive planographic printing plate material, and image forming method of photosensitive planographic printing plate material KONICA MINOLTA MEDICAL & GRAPHIC, INC. 2007-01-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090263744-A1 ETHYLENICALLY UNSATURATED COMPOUND, LIGHT SENSITIVE COMPOSITION, LIGHT SENSITIVE PLANOGRAPHIC PRINTING PLATE MATERIAL AND PRINTING PROCESS EMPLOYING THE SAME ELOVL1, ELOVL6, ELOVL3 SMN1; SMN2 4662/4885HSD17B10 766/4885TSHR 4820/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.