Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CTSG | P08311 | 1/20 | 0.40 |
| ▸ | CMA1 | P23946 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9819272 | 0.89 | SLC6A2 (0.56) | KMT2AMEN1SLC6A2SLC6A4CTSG | |
| SCHEMBL9819448 | 0.81 | DRD2 (0.52) | ALDH1A1KMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL10120650 | 0.81 | PKM (0.49) | PKMALDH1A1KMT2AHPGDMEN1 | |
| SCHEMBL9819344 | 0.80 | DRD2 (0.48) | ALDH1A1KMT2AHPGDMEN1MAPT | |
| SCHEMBL25575682 | 0.78 | L3MBTL1 (0.54) | ALDH1A1HPGDKDM4EMAPTL3MBTL1 | |
| SCHEMBL7816315 | 0.78 | ALDH1A1 (0.56) | PKMALDH1A1KMT2AHPGDMEN1 | |
| SCHEMBL9819189 | 0.76 | SRD5A1 (0.44) | KMT2ALMNAPOLBGAA | |
| SCHEMBL6418503 | 0.75 | MEN1 (0.59) | ALDH1A1KMT2AHPGDMEN1SMN1; SMN2 | |
| SCHEMBL10973333 | 0.75 | DDB1 (0.51) | ALDH1A1KMT2AHPGDMEN1KDM4E | |
| SCHEMBL9819213 | 0.74 | KMT2A (0.43) | KMT2AMEN1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0162669-B1 | ANTICONVULSIVE COMPOUNDS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-12-11 | — | — | EP | disclosed |
| US-4588729-A | Treating convulsions with dihydrouracil derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1986-05-13 | — | — | US | disclosed |
| EP-0162669-A2 | Anticonvulsive compounds | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1985-11-27 | — | — | EP | disclosed |