Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CXCR4 | P61073 | 6/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.42 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | CCR2 | P41597 | 1/20 | 0.41 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4692001 | 0.92 | MEN1 (0.47) | SMN1; SMN2CXCR4L3MBTL1MEN1KMT2A | |
| SCHEMBL10765650 | 0.86 | L3MBTL1 (0.59) | SMN1; SMN2CXCR4L3MBTL1SLC6A2SLC6A4 | |
| SCHEMBL18076484 | 0.82 | GAA (0.53) | SMN1; SMN2L3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL4786883 | 0.79 | SMN1; SMN2 (0.73) | SMN1; SMN2CXCR4L3MBTL1MEN1KMT2A | |
| SCHEMBL10399987 | 0.78 | L3MBTL1 (0.67) | SMN1; SMN2L3MBTL1MEN1KMT2AHRH3 | |
| SCHEMBL24648953 | 0.78 | MGLL (0.43) | SMN1; SMN2CXCR4L3MBTL1MEN1KMT2A | |
| SCHEMBL14863940 | 0.78 | HTR2C (0.43) | SMN1; SMN2CXCR4L3MBTL1MEN1KMT2A | |
| SCHEMBL20129619 | 0.78 | ALDH1A1 (0.42) | SMN1; SMN2CXCR4L3MBTL1MEN1KMT2A | |
| SCHEMBL25271016 | 0.78 | ALDH1A1 (0.42) | SMN1; SMN2CXCR4L3MBTL1HRH3ALDH1A1 | |
| SCHEMBL4786748 | 0.78 | HTR2C (0.49) | CXCR4L3MBTL1MEN1KMT2AHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009119528-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-10-01 | — | — | WO | disclosed |