Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | TACR1 | P25103 | 2/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | FPR2 | P25090 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.45 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9703791 | 0.80 | CYP3A4 (0.53) | MEN1KMT2AMAPTALDH1A1CA2 | |
| SCHEMBL8716574 | 0.77 | SIGMAR1 (0.52) | MEN1KMT2AHTTFPR2RAB9A | |
| SCHEMBL13664869 | 0.75 | SIGMAR1 (0.46) | MEN1KMT2AHTTFPR2L3MBTL1 | |
| SCHEMBL7815227 | 0.73 | FNTA (0.51) | MEN1KMT2ATACR1TRPV1HPGD | |
| SCHEMBL6403394 | 0.73 | KMT2A (0.63) | MEN1KMT2AHPGDMAPTL3MBTL1 | |
| SCHEMBL5866871 | 0.73 | ALDH1A1 (0.71) | MEN1KMT2AHPGDMAPTHTT | |
| SCHEMBL31705983 | 0.73 | ALDH1A1 (0.57) | MEN1KMT2AMAPTHTTFPR2 | |
| SCHEMBL6078622 | 0.73 | TSHR (0.62) | MEN1KMT2ATRPV1HPGDALDH1A1 | |
| SCHEMBL4415399 | 0.72 | OPRK1 (0.51) | MEN1KMT2ATACR1HPGDMAPT | |
| SCHEMBL4415396 | 0.72 | OPRK1 (0.51) | MEN1KMT2ATACR1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009119528-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-10-01 | — | — | WO | disclosed |