Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.52 |
| ▸ | FPR2 | P25090 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.49 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | MC4R | P32245 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13664869 | 0.80 | SIGMAR1 (0.46) | SIGMAR1FPR2MEN1KMT2ALMNA | |
| SCHEMBL11581309 | 0.79 | FPR2 (0.74) | FPR2MEN1KMT2ALMNAKCNH2 | |
| SCHEMBL903704 | 0.79 | SIGMAR1 (0.63) | SIGMAR1MEN1KMT2ATAAR1SLC18A2 | |
| SCHEMBL12744490 | 0.78 | ALDH1A1 (0.63) | MEN1KMT2ALMNAHTR1AADRA2B | |
| SCHEMBL9320616 | 0.77 | SIGMAR1 (0.53) | SIGMAR1TAAR1SLC18A2ADRB2ADRB1 | |
| SCHEMBL3905889 | 0.77 | SIGMAR1 (0.54) | SIGMAR1MEN1KMT2ATAAR1SLC18A2 | |
| SCHEMBL5009568 | 0.77 | GAA (0.45) | SIGMAR1MEN1KMT2ALMNATAAR1 | |
| SCHEMBL13664802 | 0.77 | MEN1 (0.50) | FPR2MEN1KMT2ARAB9AHTT | |
| SCHEMBL21424571 | 0.76 | ALDH1A1 (0.54) | MEN1KMT2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL29020992 | 0.76 | SIGMAR1 (0.55) | SIGMAR1MEN1KMT2ATAAR1SLC18A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |