Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | FPR2 | P25090 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.41 |
| ▸ | G6PD | P11413 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8716574 | 0.80 | SIGMAR1 (0.52) | SIGMAR1FPR2MEN1KMT2ATDP1 | |
| SCHEMBL13664860 | 0.78 | MMP8 (0.41) | EPHX2MEN1KMT2AKCNH2TMEM97 | |
| SCHEMBL13664802 | 0.75 | MEN1 (0.50) | FPR2MEN1KMT2APLA2G1BATG4B | |
| SCHEMBL13664721 | 0.74 | MAOA (0.51) | SIGMAR1MEN1KMT2ATDP1ATM | |
| SCHEMBL13664857 | 0.73 | UBE2M (0.41) | SIGMAR1EPHX2FPR2MEN1KMT2A | |
| SCHEMBL16362506 | 0.73 | TMEM97 (0.71) | SIGMAR1MEN1KMT2APOLBATM | |
| SCHEMBL11511690 | 0.71 | MEN1 (0.60) | FPR2MEN1KMT2ATDP1PLA2G1B | |
| SCHEMBL12744490 | 0.71 | ALDH1A1 (0.63) | EPHX2MEN1KMT2ATDP1POLB | |
| SCHEMBL5784665 | 0.70 | MEN1 (0.64) | SIGMAR1MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL11442742 | 0.70 | MMP8 (0.44) | SIGMAR1EPHX2TDP1POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009119528-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-10-01 | — | — | WO | disclosed |