Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
| ▸ | SNCA | P37840 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | NT5E | P21589 | 1/20 | 0.32 |
| ▸ | CASP6 | P55212 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5006716 | 0.98 | RXRA (0.35) | RXRARXRBRXRGSNCAALDH1A1 | |
| SCHEMBL136846 | 0.77 | S1PR3 (0.30) | RXRARXRBRXRGS1PR3 | |
| SCHEMBL137433 | 0.73 | RXRA (0.30) | RXRARXRBRXRG | |
| SCHEMBL29869219 | 0.72 | RXRA (0.37) | RXRARXRBRXRGSNCAALDH1A1 | |
| SCHEMBL47326 | 0.72 | RXRA (0.37) | RXRARXRBRXRGSNCAALDH1A1 | |
| SCHEMBL559919 | 0.71 | LMNA (0.36) | RXRARXRBRXRGSNCAALDH1A1 | |
| SCHEMBL224968 | 0.71 | RXRA (0.36) | RXRARXRBRXRGSNCAALDH1A1 | |
| Potassium SCHEMBL559580 | 0.71 | RXRA (0.36) | RXRARXRBRXRGSNCAALDH1A1 | |
| SCHEMBL2721236 | 0.71 | RXRA (0.36) | RXRARXRBRXRGSNCAALDH1A1 | |
| SCHEMBL135181 | 0.70 | RXRA (0.30) | RXRARXRBRXRGALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240132948-A1 | Cyanine Dyes | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | 2024-04-25 | — | — | US | disclosed |
| US-11624089-B2 | Cyanine dyes | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2023-04-11 | — | — | US | disclosed |
| US-20230085980-A1 | A Theranostic Probe and its Use for Targeting and/or Labeling the EGFR Kinase and/or the Cells Expressing EGFR or its Family Members | TIANJIN UNIVERSITY (CN) | 2023-03-23 | — | — | US | disclosed |
| US-20200232023-A1 | CYANINE DYES | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | 2020-07-23 | — | — | US | disclosed |
| US-10392659-B2 | Cyanine dyes | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2019-08-27 | — | — | US | disclosed |
| US-20180156810-A1 | FLUORESCENT COMPOUNDS | BIOTIUM, INC. | 2018-06-07 | — | — | US | disclosed |
| US-9920365-B2 | Functionalized cyanine dyes (PEG) | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2018-03-20 | — | — | US | disclosed |
| US-9791450-B2 | Fluorescent compounds | BIOTIUM, INC. (US) | 2017-10-17 | — | — | US | disclosed |
| US-20170183501-A1 | Cyanine Dyes | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | 2017-06-29 | — | — | US | disclosed |
| US-9441270-B2 | Cyanine dyes | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2016-09-13 | — | — | US | disclosed |
| EP-1112254-A2 | CYANINE DYES AND SYNTHESIS METHODS THEREOF | NEN Life Science Products, Inc. (US) | 2001-07-04 | — | — | EP | disclosed |
| US-6224644-B1 | CYANINE DYES INCLUDES FREE OR PROTECTED THIOL, AMINE OR HYDROXY SUBSTITUENT CAPABLE OF REACTING WITH A TARGET MOLECULE THROUGH A NEUCLOPHILIC DISPLACEMENT, USEFUL IN LABELING A VARIETY OF TARGET MOLECULES | NEN LIFE SCIENCE PRODUCTS, INC. | 2001-05-01 | — | — | US | disclosed |
| US-6204389-B1 | DEBLOCKING; NUCLEOPHILIC DISPLACEMENT | NEN LIFE SCIENCE PRODUCTS, INC. | 2001-03-20 | — | — | US | disclosed |
| US-6197956-B1 | FLUORESCENT BENZIMIDAZOLE, BENZOTHIAZOLE, BENZOXAZOLE, BENZOTHIAZINE, BENZOXAZINE AND QUINOLINE DYES | NEN LIFE SCIENCE PRODUCTS, INC. | 2001-03-06 | — | — | US | disclosed |
| EP-1078023-A1 | LUMINESCENT COMPOUNDS | Terpetschnig, Ewald A. (US) | 2001-02-28 | — | — | EP | disclosed |
| WO-2000063296-A2 | CYANINE DYES AND SYNTHESIS METHODS THEREOF | NEN LIFE SCIENCE PRODUCTS, INC. (US) | 2000-10-26 | — | — | WO | disclosed |
| US-6002003-A | Cyanine dye activating group with improved coupling selectivity | BECKMAN INSTRUMENTS, INC. (US) | 1999-12-14 | — | — | US | disclosed |
| WO-1999051702-A1 | LUMINESCENT COMPOUNDS | TERPETSCHNIG EWALD A (US) | 1999-10-14 | — | — | WO | disclosed |
| EP-0943918-A1 | Fluorescent labelling complexes with large Stokes' shifts formed by coupling together cyanine and other fluorochromes capable of resonance energy transfer | CARNEGIE-MELLON UNIVERSITY (US) | 1999-09-22 | — | — | EP | disclosed |
| EP-0747700-A2 | Fluorescent labelling complexes with large stokes shifts formed by coupling together cyanine and other fluorochromes capable of resonance energy transfer | CARNEGIE-MELLON UNIVERSITY (US) | 1996-12-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240132948-A1 | Cyanine Dyes | ABCG2, IK, ACR | RXRA 2390/4885RXRB 2432/4885RXRG 1959/4885 |
| US-10392659-B2 | Cyanine dyes | ABCG2, IK, ACR | RXRA 2390/4885RXRB 2432/4885RXRG 1959/4885 |
| US-11624089-B2 | Cyanine dyes | ABCG2, IK, ACR | RXRA 2390/4885RXRB 2432/4885RXRG 1959/4885 |
| US-20200232023-A1 | CYANINE DYES | ABCG2, IK, ACR | RXRA 2390/4885RXRB 2432/4885RXRG 1959/4885 |
| US-20230085980-A1 | A Theranostic Probe and its Use for Targeting and/or Labeling the EGFR Kinase and/or the Cells Expressing EGFR or its Family Members | EGFR, ERBB2, ERBB3 | RXRA 3487/4885RXRB 3366/4885RXRG 3160/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.