Sugi Predict

Sugi Predict / Compounds / SCHEMBL559919

SCHEMBL559919

SCHEMBL559919

CC1=[N+](C)c2ccc(S(=O)(=O)O)cc2C1(C)C

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 5/20 0.36
▸ MAPT P10636 5/20 0.36
▸ MEN1 O00255 4/20 0.36
▸ KMT2A Q03164 4/20 0.36
▸ TDP1 Q9NUW8 3/20 0.36
▸ THRB P10828 3/20 0.36
▸ RECQL P46063 3/20 0.36
▸ KDM4E B2RXH2 3/20 0.36
▸ HTT P42858 2/20 0.36
▸ APEX1 P27695 1/20 0.36
▸ RXRA P19793 1/20 0.36
▸ RXRB P28702 1/20 0.36
▸ RXRG P48443 1/20 0.36
▸ SNCA P37840 1/20 0.36
▸ ALDH1A1 P00352 7/20 0.35
▸ HSD17B10 Q99714 4/20 0.35
▸ CA1 P00915 3/20 0.35
▸ CA2 P00918 3/20 0.35
▸ CA12 O43570 2/20 0.35
▸ CA7 P43166 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29929178 0.85 TDP1 (0.42) LMNAMAPTMEN1KMT2ATDP1
SCHEMBL559385 0.85 TDP1 (0.42) LMNAMAPTMEN1KMT2ATDP1
SCHEMBL17250078 0.84 MAPT (0.42) LMNAMAPTMEN1KMT2ATDP1
SCHEMBL1367336 0.80 LMNA (0.61) LMNAMAPTMEN1KMT2ATDP1
SCHEMBL14781535 0.80 ALDH1A1 (0.33) LMNATDP1KDM4ERXRARXRB
Water SCHEMBL6796016 0.79 LMNA (0.60) LMNAMAPTMEN1KMT2ATDP1
SCHEMBL10093777 0.79 LMNA (0.46) LMNAMAPTMEN1KMT2ATDP1
SCHEMBL26319348 0.79 VDR (0.45) LMNAMAPTMEN1KMT2ATDP1
Sulfuric Acid SCHEMBL4614646 0.78 MAPT (0.42) LMNAMAPTTDP1KDM4EAPEX1
SCHEMBL12146299 0.78 TDP1 (0.58) LMNAMAPTMEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4234566-A1 MODIFIED NUCLEOSIDE OR NUCLEOTIDE BGI Shenzhen (CN) 2023-08-30 — — EP disclosed
US-20160356681-A1 MODIFIED CARBOCYANINE DYES AND THEIR CONJUGATES Life Technologies Corporation 2016-12-08 — — US disclosed
US-9423323-B2 Modified carbocyanine dyes and their conjugates Life Technologies Corporation (US) 2016-08-23 — — US disclosed
US-20150259535-A1 Fluorescent dyes ANASPEC INC (US) 2015-09-17 — — US disclosed
US-20150247785-A1 MODIFIED CARBOCYANINE DYES AND THEIR CONJUGATES Life Technologies Corporation 2015-09-03 — — US disclosed
US-9110069-B2 Luminescent compounds SETA BIOMEDICALS, LLC (US) 2015-08-18 — — US disclosed
US-20150218380-A1 MODIFIED CARBOCYANINE DYES AND THEIR CONJUGATES Life Technologies Corporation 2015-08-06 — — US disclosed
US-9018396-B2 Modified carbocyanine dyes and their conjugates Life Technologies Corporation (US) 2015-04-28 — — US disclosed
US-8999690-B2 Kits for analysis of biological samples ANASPEC INCORPORATED (US) 2015-04-07 — — US disclosed
EP-1322710-B2 MODIFIED CARBOCYANINE DYES AND THEIR CONJUGATES LIFE TECHNOLOGIES CORP (US) 2015-02-18 — — EP disclosed
US-6974873-B2 Modified carbocyanine dyes and their conjugates MOLECULAR PROBES, INC. (US) 2005-12-13 — — US disclosed
US-20050202565-A1 Luminescent compounds SETA BIOMEDICALS, LLC 2005-09-15 — — US disclosed
US-20040166515-A1 Luminescent compounds TERPETSCHNIG, EWALD A. 2004-08-26 — — US disclosed
US-20030235846-A1 Luminescent compounds TERPTETSCHNIG, EWALD A. 2003-12-25 — — US disclosed
EP-1078023-A4 LUMINESCENT COMPOUNDS TERPETSCHNIG EWALD A (US) 2003-03-26 — — EP disclosed
US-6538129-B1 Luminescent compounds Terpetschnig, Ewald A. 2003-03-25 — — US disclosed
US-20020077487-A1 Modified carbocyanine dyes and their conjugates MOLECULAR PROBES, INC. 2002-06-20 — — US disclosed
US-20020064794-A1 Modified carbocyanine dyes and their conjugates MOLECULAR PROBES, INC. 2002-05-30 — — US disclosed
EP-1078023-A1 LUMINESCENT COMPOUNDS Terpetschnig, Ewald A. (US) 2001-02-28 — — EP disclosed
WO-1999051702-A1 LUMINESCENT COMPOUNDS TERPETSCHNIG EWALD A (US) 1999-10-14 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020077487-A1 Modified carbocyanine dyes and their conjugates IK, CBR3, DRD5 LMNA 2822/4885MAPT 2463/4885MEN1 1243/4885
US-20030235846-A1 Luminescent compounds CROCC, NR2E1, NDC1 LMNA 813/4885MAPT 4435/4885MEN1 4116/4885
US-20160356681-A1 MODIFIED CARBOCYANINE DYES AND THEIR CONJUGATES IK, CBR3, DRD5 LMNA 2822/4885MAPT 2463/4885MEN1 1243/4885
US-20150218380-A1 MODIFIED CARBOCYANINE DYES AND THEIR CONJUGATES IK, CBR3, DRD5 LMNA 2822/4885MAPT 2463/4885MEN1 1243/4885
US-20150247785-A1 MODIFIED CARBOCYANINE DYES AND THEIR CONJUGATES IK, CBR3, DRD5 LMNA 2822/4885MAPT 2463/4885MEN1 1243/4885
US-20040166515-A1 Luminescent compounds RORC, NR2E3, RORB LMNA 1196/4885MAPT 4542/4885MEN1 3748/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.