Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13675569 | 0.84 | ALOX5 (0.52) | MAPTTDP1SMN1; SMN2RAB9AKDM4E | |
| SCHEMBL13675568 | 0.84 | L3MBTL1 (0.45) | KDM4EALDH1A1TRPM8HPGDPTGDR2 | |
| SCHEMBL13675833 | 0.73 | MAPT (0.42) | MAPTTDP1SMN1; SMN2NFKB1RAB9A | |
| SCHEMBL3825255 | 0.73 | TRPM8 (0.52) | MAPTTDP1SMN1; SMN2NFKB1RAB9A | |
| SCHEMBL3372237 | 0.72 | MAPT (0.55) | MAPTTDP1SMN1; SMN2NFKB1RAB9A | |
| SCHEMBL13462298 | 0.70 | MAPT (0.51) | MAPTTDP1SMN1; SMN2NFKB1RAB9A | |
| SCHEMBL1180747 | 0.69 | RAB9A (0.59) | MAPTTDP1SMN1; SMN2NFKB1RAB9A | |
| SCHEMBL8715461 | 0.68 | CYP19A1 (0.59) | MAPTTDP1SMN1; SMN2NFKB1RAB9A | |
| SCHEMBL2090795 | 0.67 | MAPT (1.00) | MAPTTDP1SMN1; SMN2NFKB1RAB9A | |
| SCHEMBL30161523 | 0.67 | MAPT (1.00) | MAPTTDP1SMN1; SMN2NFKB1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090270456-A1 | Novel chemical compounds | HASEGAWA MASAICHI | 2009-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090270456-A1 | Novel chemical compounds | HIPK3, HIPK2, HIPK1 | MAPT 1801/4885TDP1 1695/4885SMN1; SMN2 3016/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.