Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 4/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.39 |
| ▸ | NQO2 | P16083 | 4/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680494 | 0.84 | ALDH1A1 (0.46) | GSK3BPPARDMAPTALDH1A1HPGD | |
| SCHEMBL5655892 | 0.78 | GSK3B (0.64) | GSK3BMAPTALDH1A1HPGDMEN1 | |
| SCHEMBL9152657 | 0.77 | MLYCD (0.53) | MLYCDMAPTALDH1A1HPGDMEN1 | |
| SCHEMBL5206193 | 0.77 | HSD17B1 (0.49) | MAPTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL2389064 | 0.76 | FAAH (0.37) | GSK3BPPARDMAPTALDH1A1HPGD | |
| SCHEMBL13680892 | 0.76 | ALDH1A1 (0.44) | MLYCDPPARDMAPTALDH1A1HPGD | |
| SCHEMBL13680465 | 0.75 | GSK3B (0.61) | GSK3BMAPTALDH1A1HPGDMEN1 | |
| SCHEMBL13680452 | 0.75 | GSK3B (0.61) | GSK3BMAPTALDH1A1HPGDMEN1 | |
| SCHEMBL870352 | 0.75 | MLYCD (0.57) | MLYCDGSK3BMAPTALDH1A1HPGD | |
| SCHEMBL4449884 | 0.74 | MAPT (0.56) | MLYCDMAPTALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |