Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GSK3B | P49841 | 4/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | NQO2 | P16083 | 3/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680462 | 0.84 | MLYCD (0.46) | ALDH1A1HPGDSMN1; SMN2GSK3BPPARD | |
| SCHEMBL13680452 | 0.80 | GSK3B (0.61) | ALDH1A1HPGDSMN1; SMN2GSK3BNQO2 | |
| SCHEMBL13680465 | 0.80 | GSK3B (0.61) | ALDH1A1HPGDSMN1; SMN2GSK3BNQO2 | |
| SCHEMBL13680703 | 0.79 | ALDH1A1 (0.46) | ALDH1A1HPGDSMN1; SMN2GSK3BPPARD | |
| SCHEMBL13680503 | 0.79 | GSK3B (0.62) | ALDH1A1HPGDSMN1; SMN2GSK3BNQO2 | |
| SCHEMBL10626283 | 0.77 | ALDH1A1 (0.64) | ALDH1A1HPGDSMN1; SMN2HDAC4ERN1 | |
| SCHEMBL23197679 | 0.77 | TDP1 (0.56) | ALDH1A1HPGDSMN1; SMN2GSK3BNQO2 | |
| SCHEMBL13680504 | 0.76 | PLK1 (0.50) | ALDH1A1HPGDSMN1; SMN2GSK3BNQO2 | |
| SCHEMBL5655892 | 0.76 | GSK3B (0.64) | ALDH1A1HPGDSMN1; SMN2GSK3BMAPT | |
| SCHEMBL13680561 | 0.76 | RAB9A (0.59) | ALDH1A1HPGDSMN1; SMN2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |