Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | CNR1 | P21554 | 1/20 | 0.55 |
| ▸ | CSF1R | P07333 | 1/20 | 0.53 |
| ▸ | FLT1 | P17948 | 1/20 | 0.53 |
| ▸ | FLT3 | P36888 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.49 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.48 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680515 | 0.89 | FAAH (0.66) | FAAHALDH1A1CYP3A4MAPK1CNR1 | |
| SCHEMBL5425007 | 0.86 | NPC1 (0.55) | ALDH1A1MAPK1CNR1CSF1RFLT1 | |
| SCHEMBL12812645 | 0.85 | KDM4E (0.55) | ALDH1A1CNR1CSF1RFLT1FLT3 | |
| SCHEMBL9127154 | 0.84 | HSD17B1 (0.55) | CYP3A4CNR1SMN1; SMN2HSD17B1HSD17B2 | |
| SCHEMBL8265472 | 0.83 | HSD17B10 (0.66) | ALDH1A1CNR1CSF1RFLT1FLT3 | |
| SCHEMBL2092941 | 0.83 | SMN1; SMN2 (0.68) | ALDH1A1SMN1; SMN2KMT2AHPGD | |
| SCHEMBL7251623 | 0.82 | SMN1; SMN2 (0.72) | ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL13680497 | 0.82 | KIF11 (0.69) | CNR1CSF1RFLT1FLT3KMT2A | |
| SCHEMBL2095614 | 0.81 | ALDH1A1 (0.79) | FAAHALDH1A1CYP3A4MAPK1SMN1; SMN2 | |
| SCHEMBL30589563 | 0.81 | ALDH1A1 (0.79) | FAAHALDH1A1CYP3A4MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |