Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680574 | 0.85 | RAB9A (0.49) | TSHRRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL13680522 | 0.84 | RAB9A (0.55) | RAB9AMEN1KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL13680537 | 0.82 | KIF11 (0.54) | RAB9AMEN1KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL13680489 | 0.81 | SMN1; SMN2 (0.47) | RAB9AMEN1KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL13680523 | 0.81 | RAB9A (0.51) | RAB9AMEN1KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL13680528 | 0.78 | ALDH1A1 (0.45) | RAB9AMEN1KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL13680940 | 0.77 | TP53 (0.45) | RAB9AMEN1KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL13680741 | 0.77 | KIF11 (0.43) | TSHRRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL8198560 | 0.76 | CYP3A4 (0.60) | RAB9AMEN1KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL13680526 | 0.74 | RAB9A (0.54) | TSHRRAB9AKMT2ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |