Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.55 |
| ▸ | NPC1 | O15118 | 5/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 8/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | STAT1 | P42224 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | SULT1A1 | P50225 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680537 | 0.86 | KIF11 (0.54) | RAB9ANPC1SMN1; SMN2L3MBTL1KMT2A | |
| SCHEMBL13680489 | 0.85 | SMN1; SMN2 (0.47) | RAB9ANPC1SMN1; SMN2L3MBTL1KMT2A | |
| SCHEMBL13680523 | 0.85 | RAB9A (0.51) | RAB9ANPC1SMN1; SMN2L3MBTL1KMT2A | |
| SCHEMBL13680476 | 0.84 | TSHR (0.47) | RAB9ANPC1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL13680574 | 0.80 | RAB9A (0.49) | RAB9ANPC1SMN1; SMN2KMT2AGFER | |
| SCHEMBL13680741 | 0.80 | KIF11 (0.43) | RAB9ANPC1SMN1; SMN2KMT2AGAA | |
| SCHEMBL8198560 | 0.79 | CYP3A4 (0.60) | RAB9ANPC1SMN1; SMN2KMT2AGAA | |
| SCHEMBL13680487 | 0.79 | ALDH1A1 (0.49) | RAB9ANPC1SMN1; SMN2KMT2AGAA | |
| SCHEMBL7905176 | 0.77 | CYP3A4 (0.58) | RAB9ANPC1SMN1; SMN2KMT2AGAA | |
| SCHEMBL13680747 | 0.77 | CYP2C9 (0.42) | RAB9ANPC1L3MBTL1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |