Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CCR1 | P32246 | 1/20 | 0.47 |
| ▸ | CCR8 | P51685 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680556 | 0.86 | MEN1 (0.46) | RAB9ANPC1MEN1KMT2ACCR1 | |
| SCHEMBL13680474 | 0.83 | ALDH1A1 (0.55) | RAB9ANPC1MEN1KMT2ALMNA | |
| SCHEMBL13680475 | 0.83 | RAB9A (0.56) | RAB9ANPC1MEN1KMT2ALMNA | |
| SCHEMBL3422361 | 0.78 | CCR1 (0.75) | RAB9AMEN1KMT2AHSD17B10CCR1 | |
| SCHEMBL13680472 | 0.78 | CCR1 (0.52) | RAB9ANPC1HSD17B10CCR1CCR8 | |
| SCHEMBL2614971 | 0.78 | MAPK14 (0.60) | RAB9ANPC1MEN1KMT2ACCR1 | |
| SCHEMBL4960001 | 0.77 | LMNA (0.71) | MEN1KMT2ALMNAGAAHSD17B10 | |
| SCHEMBL22939579 | 0.76 | MAPT (0.59) | RAB9ANPC1MEN1KMT2ALMNA | |
| SCHEMBL6590103 | 0.75 | LMNA (0.57) | RAB9ANPC1MEN1KMT2ALMNA | |
| SCHEMBL3134631 | 0.75 | CCR1 (0.52) | RAB9ANPC1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |