Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CCR1 | P32246 | 1/20 | 0.46 |
| ▸ | CCR8 | P51685 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | TGFBR1 | P36897 | 7/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680502 | 0.86 | RAB9A (0.60) | MEN1KMT2ANPC1RAB9ACCR1 | |
| SCHEMBL13680474 | 0.82 | ALDH1A1 (0.55) | MEN1KMT2ANPC1RAB9ACCR1 | |
| SCHEMBL13680475 | 0.82 | RAB9A (0.56) | MEN1KMT2ANPC1RAB9ACCR1 | |
| SCHEMBL27768099 | 0.82 | PARP1 (0.48) | MEN1KMT2AKIF11PARP1TGFBR1 | |
| SCHEMBL27747196 | 0.81 | MEN1 (0.44) | MEN1KMT2ANPC1KIF11PARP1 | |
| SCHEMBL27747193 | 0.81 | SCN9A (0.47) | MEN1KMT2ANPC1RAB9AKIF11 | |
| SCHEMBL12270020 | 0.79 | TGFBR1 (0.50) | CCR1CCR8CYP2A6TGFBR1MAPK14 | |
| SCHEMBL29949633 | 0.79 | TGFBR1 (0.50) | CCR1CCR8CYP2A6TGFBR1MAPK14 | |
| SCHEMBL3422361 | 0.77 | CCR1 (0.75) | MEN1KMT2ARAB9ACCR1CCR8 | |
| SCHEMBL27768366 | 0.77 | F2 (0.47) | MEN1KMT2ANPC1RAB9ASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |