Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.43 |
| ▸ | CCR1 | P32246 | 1/20 | 0.43 |
| ▸ | CCR8 | P51685 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680502 | 0.83 | RAB9A (0.60) | RAB9ANPC1ALDH1A1PKMSMN1; SMN2 | |
| SCHEMBL13680556 | 0.82 | MEN1 (0.46) | RAB9ANPC1ALDH1A1KMT2AMEN1 | |
| SCHEMBL13680474 | 0.79 | ALDH1A1 (0.55) | RAB9ANPC1ALDH1A1PKMSMN1; SMN2 | |
| SCHEMBL13680473 | 0.77 | TGFBR1 (0.48) | ALDH1A1SMN1; SMN2KDM4ETSHRKMT2A | |
| SCHEMBL13680842 | 0.77 | RAB9A (0.45) | RAB9ANPC1ALDH1A1PKMSMN1; SMN2 | |
| SCHEMBL3422361 | 0.75 | CCR1 (0.75) | RAB9AALDH1A1MAPTKMT2AHPGD | |
| SCHEMBL6450091 | 0.75 | RAB9A (1.00) | RAB9AALDH1A1PKMTSHRKMT2A | |
| SCHEMBL30738654 | 0.74 | RAB9A (0.73) | RAB9ANPC1ALDH1A1PKMSMN1; SMN2 | |
| SCHEMBL2614971 | 0.74 | MAPK14 (0.60) | RAB9ANPC1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL13680483 | 0.73 | TSHR (0.49) | RAB9ANPC1SMN1; SMN2MAPTNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |