Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 10/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 2/20 | 0.46 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12318239 | 0.85 | NPC1 (0.62) | CNR1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL13537053 | 0.85 | SMN1; SMN2 (0.49) | NPC1RAB9AMAPTSMN1; SMN2NFKB1 | |
| SCHEMBL11653085 | 0.81 | MGLL (0.58) | CNR1SMN1; SMN2FAAHALDH1A1CYP3A4 | |
| SCHEMBL13680584 | 0.78 | GABRG2 (0.53) | NPC1RAB9AMAPK1CYP2A6TP53 | |
| SCHEMBL13680515 | 0.77 | FAAH (0.66) | CNR1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL13680686 | 0.77 | CYP2A6 (0.45) | NPC1RAB9AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL2094875 | 0.77 | MGLL (0.68) | CNR1FAAHMEN1KMT2A | |
| SCHEMBL14636653 | 0.76 | CNR1 (0.47) | CNR1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL716889 | 0.76 | MAPK1 (0.62) | NPC1RAB9AMAPTSMN1; SMN2FAAH | |
| SCHEMBL13680552 | 0.75 | CYP2A6 (0.53) | FYNKDRCYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |