Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 5/20 | 0.41 |
| ▸ | BCHE | P06276 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680520 | 0.82 | LMNA (0.53) | RAB9ATSHRALDH1A1GAAPKM | |
| SCHEMBL13680467 | 0.81 | KIF11 (0.46) | RAB9AALDH1A1GAAPKMKMT2A | |
| SCHEMBL13680512 | 0.78 | ALDH1A1 (0.45) | RAB9AALDH1A1GAAPKMKMT2A | |
| SCHEMBL6450091 | 0.77 | RAB9A (1.00) | RAB9ATSHRALDH1A1GAAPKM | |
| SCHEMBL13680494 | 0.76 | ALDH1A1 (0.46) | RAB9AALDH1A1GAAPKMKMT2A | |
| SCHEMBL13680895 | 0.76 | ALDH1A1 (0.48) | RAB9ATSHRALDH1A1GAAPKM | |
| P-Tolyl Dimethylcarbamate SCHEMBL360147 | 0.74 | RAB9A (0.83) | RAB9ATSHRALDH1A1GAAPKM | |
| SCHEMBL23197679 | 0.73 | TDP1 (0.56) | RAB9ATSHRALDH1A1GAAKMT2A | |
| SCHEMBL30738654 | 0.73 | RAB9A (0.73) | RAB9ATSHRALDH1A1GAAPKM | |
| SCHEMBL13680560 | 0.72 | GSK3B (0.59) | RAB9ATSHRALDH1A1GAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |