Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.46 |
| ▸ | NQO2 | P16083 | 5/20 | 0.44 |
| ▸ | GSK3B | P49841 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PRNP | P04156 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.38 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680520 | 0.85 | LMNA (0.53) | NQO2GSK3BKDM4EALDH1A1MAPT | |
| SCHEMBL13680561 | 0.81 | RAB9A (0.59) | KDM4EALDH1A1MAPTPKMHPGD | |
| SCHEMBL13680512 | 0.81 | ALDH1A1 (0.45) | NQO2GSK3BKDM4EALDH1A1MAPT | |
| SCHEMBL13680503 | 0.77 | GSK3B (0.62) | NQO2GSK3BKDM4EALDH1A1HPGD | |
| SCHEMBL23197679 | 0.75 | TDP1 (0.56) | NQO2GSK3BKDM4EALDH1A1MAPT | |
| SCHEMBL7647138 | 0.74 | KIF11 (0.59) | KIF11ALDH1A1MAPTLMNAHSD17B10 | |
| SCHEMBL13680560 | 0.74 | GSK3B (0.59) | NQO2GSK3BKDM4EALDH1A1MAPT | |
| SCHEMBL13680488 | 0.73 | KIF11 (0.59) | KIF11GSK3BKDM4EALDH1A1MAPT | |
| SCHEMBL6284986 | 0.73 | KMT2A (0.64) | KIF11ALDH1A1MAPTPKMLMNA | |
| SCHEMBL13680879 | 0.72 | ALDH1A1 (0.48) | KIF11NQO2KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |