Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 3/20 | 0.48 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MMP7 | P09237 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | MMP14 | P50281 | 1/20 | 0.41 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28314915 | 0.81 | SMN1; SMN2 (0.48) | MAPTCTDSP1ALDH1A1GAAALOX12 | |
| SCHEMBL13680645 | 0.80 | HSD17B2 (0.51) | HSD17B2HSD17B1MAPTPOLBCTDSP1 | |
| SCHEMBL7501911 | 0.80 | ALDH1A1 (0.50) | MAPTPOLBHDAC8HDAC6ALDH1A1 | |
| SCHEMBL13680446 | 0.79 | MAPT (0.62) | HSD17B2HSD17B1MAPTPOLBCTDSP1 | |
| SCHEMBL13680641 | 0.79 | HSD17B1 (0.50) | HSD17B2HSD17B1MAPTPOLBCTDSP1 | |
| SCHEMBL6561397 | 0.77 | ACHE (0.61) | HSD17B2HSD17B1POLBENPP3FNTA | |
| SCHEMBL13680639 | 0.76 | HSD17B2 (0.55) | HSD17B2HSD17B1MAPTPOLBCTDSP1 | |
| SCHEMBL13681333 | 0.75 | HSD17B2 (0.50) | HSD17B2HSD17B1MAPTPOLBCTDSP1 | |
| SCHEMBL18797759 | 0.74 | ACHE (0.65) | HSD17B2HSD17B1ENPP3FNTAFNTB | |
| SCHEMBL9629049 | 0.74 | GAA (0.46) | MAPTPOLBHDAC2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |