Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 1/20 | 0.47 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.46 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.46 |
| ▸ | PLK1 | P53350 | 3/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | GPR52 | Q9Y2T5 | 2/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680788 | 0.85 | MAPT (0.50) | BCL2AOC3GPR52MAPTSMN1; SMN2 | |
| SCHEMBL13680789 | 0.84 | ERN1 (0.50) | BCL2ALDH1A1MAPTRAB9AMEN1 | |
| SCHEMBL13681324 | 0.83 | BCL2 (0.63) | BCL2AOC3GPR52 | |
| SCHEMBL13680794 | 0.82 | AOC3 (0.53) | BCL2MKNK1MKNK2AOC3GPR52 | |
| SCHEMBL13680803 | 0.82 | CNR1 (0.44) | AOC3ALDH1A1 | |
| SCHEMBL13680801 | 0.81 | ERN1 (0.50) | BCL2AOC3GPR52ALDH1A1LMNA | |
| SCHEMBL13680793 | 0.81 | BCHE (0.47) | ALDH1A1NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL13680796 | 0.78 | AOC3 (0.56) | AOC3ALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL13680790 | 0.78 | FFAR1 (0.45) | BCL2GPR52 | |
| SCHEMBL418611 | 0.77 | GPR52 (0.50) | BCL2AOC3GPR52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |