Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 8/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.41 |
| ▸ | PIP4K2B | P78356 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.40 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGAV | P06756 | 1/20 | 0.40 |
| ▸ | CDK7 | P50613 | 1/20 | 0.39 |
| ▸ | CCNH | P51946 | 1/20 | 0.39 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680796 | 0.87 | AOC3 (0.56) | AOC3ALDH1A1PIP4K2APIP4K2BFFAR1 | |
| SCHEMBL13680802 | 0.85 | MGLL (0.45) | AOC3FFAR1MGLL | |
| SCHEMBL13680800 | 0.84 | KIF11 (0.52) | CNR1AOC3FFAR1CSF1RFLT1 | |
| SCHEMBL13680807 | 0.84 | AOC3 (0.61) | AOC3 | |
| SCHEMBL13680795 | 0.82 | BCL2 (0.47) | AOC3ALDH1A1 | |
| SCHEMBL13680793 | 0.79 | BCHE (0.47) | ALDH1A1FFAR1 | |
| SCHEMBL13680788 | 0.77 | MAPT (0.50) | AOC3 | |
| SCHEMBL13680804 | 0.76 | HSD17B1 (0.47) | ALDH1A1PIP4K2APIP4K2B | |
| SCHEMBL13680789 | 0.76 | ERN1 (0.50) | ALDH1A1 | |
| SCHEMBL13680790 | 0.76 | FFAR1 (0.45) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |