Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 5/20 | 0.50 |
| ▸ | HSD17B2 | P37059 | 5/20 | 0.49 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.49 |
| ▸ | BCL2 | P10415 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 6/20 | 0.46 |
| ▸ | ATR | Q13535 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680788 | 0.85 | MAPT (0.50) | HSD17B2HSD17B1BCL2AOC3LMNA | |
| SCHEMBL13681324 | 0.83 | BCL2 (0.63) | ERN1BCL2AOC3GPR52 | |
| SCHEMBL13680794 | 0.82 | AOC3 (0.53) | ERN1BCL2AOC3GPR52 | |
| SCHEMBL13060851 | 0.81 | BCL2 (0.69) | ERN1HSD17B2HSD17B1BCL2AOC3 | |
| SCHEMBL13680795 | 0.81 | BCL2 (0.47) | BCL2AOC3ALDH1A1LMNAMAPK1 | |
| SCHEMBL13680789 | 0.81 | ERN1 (0.50) | ERN1BCL2ALDH1A1 | |
| SCHEMBL13680807 | 0.81 | AOC3 (0.61) | AOC3 | |
| SCHEMBL13680799 | 0.81 | ACHE (0.52) | ALDH1A1LMNA | |
| SCHEMBL13680790 | 0.78 | FFAR1 (0.45) | BCL2GPR52 | |
| SCHEMBL13005476 | 0.78 | HSD17B2 (0.51) | ERN1HSD17B2HSD17B1BCL2AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |