Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 3/20 | 0.53 |
| ▸ | ERN1 | O75460 | 2/20 | 0.47 |
| ▸ | BCL2 | P10415 | 1/20 | 0.47 |
| ▸ | GPR52 | Q9Y2T5 | 2/20 | 0.45 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.45 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.44 |
| ▸ | MKNK2 | Q9HBH9 | 3/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | ERCC5 | P28715 | 2/20 | 0.43 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13681324 | 0.87 | BCL2 (0.63) | AOC3ERN1BCL2GPR52TRIM24 | |
| SCHEMBL13680788 | 0.85 | MAPT (0.50) | AOC3BCL2GPR52TRIM24TRIM33 | |
| SCHEMBL1789918 | 0.83 | AOC3 (0.60) | AOC3BCL2ABHD6MKNK1MKNK2 | |
| SCHEMBL13680800 | 0.82 | KIF11 (0.52) | AOC3GPR52PDE4D | |
| SCHEMBL13680789 | 0.82 | ERN1 (0.50) | ERN1BCL2 | |
| SCHEMBL13680801 | 0.82 | ERN1 (0.50) | AOC3ERN1BCL2GPR52 | |
| SCHEMBL13680795 | 0.82 | BCL2 (0.47) | AOC3BCL2GPR52MKNK1MKNK2 | |
| SCHEMBL13680792 | 0.82 | MEN1 (0.42) | AOC3BCL2GPR52ABHD6 | |
| SCHEMBL8413593 | 0.81 | TAAR1 (0.44) | BCL2GPR52 | |
| SCHEMBL418611 | 0.81 | GPR52 (0.50) | AOC3BCL2GPR52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |