Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 11/20 | 0.52 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680791 | 0.86 | GAA (0.55) | ABHD6RAB9AKMT2ALMNAFFAR1 | |
| SCHEMBL13680792 | 0.83 | MEN1 (0.42) | ABHD6KMT2ALMNAFFAR1 | |
| SCHEMBL13680793 | 0.82 | BCHE (0.47) | ACHEABHD6RAB9AALDH1A1LMNA | |
| SCHEMBL13681368 | 0.81 | AOC3 (0.40) | ABHD6LMNAFFAR1 | |
| SCHEMBL13680801 | 0.81 | ERN1 (0.50) | ALDH1A1LMNA | |
| SCHEMBL13680784 | 0.80 | ABL1 (0.50) | ALDH1A1LMNAFFAR1TSHR | |
| SCHEMBL13680783 | 0.78 | FFAR1 (0.45) | FFAR1 | |
| SCHEMBL13680807 | 0.78 | AOC3 (0.61) | TSHR | |
| SCHEMBL2302446 | 0.76 | FFAR4 (0.46) | ALDH1A1FFAR1 | |
| SCHEMBL13680788 | 0.76 | MAPT (0.50) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |