Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.37 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13681368 | 0.87 | AOC3 (0.40) | ABHD6FFAR1AKR1B1FFAR4GPR52 | |
| SCHEMBL13680791 | 0.86 | GAA (0.55) | MEN1KMT2AABHD6FFAR1AKR1B1 | |
| SCHEMBL3830344 | 0.84 | KMT2A (0.58) | MEN1KMT2A | |
| SCHEMBL13680799 | 0.83 | ACHE (0.52) | KMT2AABHD6FFAR1LMNA | |
| SCHEMBL13680793 | 0.83 | BCHE (0.47) | ABHD6FFAR1LMNAGAAMAPT | |
| SCHEMBL13680794 | 0.82 | AOC3 (0.53) | ABHD6GPR52BCL2AOC3 | |
| SCHEMBL13680783 | 0.81 | FFAR1 (0.45) | FFAR1AKR1B1FFAR4GPR52F2 | |
| SCHEMBL13680784 | 0.80 | ABL1 (0.50) | FFAR1GPR52LMNA | |
| SCHEMBL2302446 | 0.79 | FFAR4 (0.46) | FFAR1AKR1B1FFAR4GPR52NR4A2 | |
| SCHEMBL13680800 | 0.78 | KIF11 (0.52) | KIF11FFAR1FFAR4GPR52GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |