Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 5/20 | 0.61 |
| ▸ | PNPLA2 | Q96AD5 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680796 | 0.86 | AOC3 (0.56) | AOC3 | |
| SCHEMBL13680803 | 0.84 | CNR1 (0.44) | AOC3 | |
| SCHEMBL13680802 | 0.84 | MGLL (0.45) | AOC3 | |
| SCHEMBL13680800 | 0.83 | KIF11 (0.52) | AOC3 | |
| SCHEMBL13680801 | 0.81 | ERN1 (0.50) | AOC3 | |
| SCHEMBL13680799 | 0.78 | ACHE (0.52) | TSHR | |
| SCHEMBL13680788 | 0.76 | MAPT (0.50) | AOC3 | |
| SCHEMBL13680841 | 0.76 | TSHR (0.40) | AOC3PNPLA2HDAC6TSHR | |
| SCHEMBL11359367 | 0.76 | AOC3 (1.00) | AOC3 | |
| SCHEMBL13680447 | 0.76 | PNPLA2 (0.62) | AOC3PNPLA2HDAC6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |